研究業績

原著論文 |総説・著書 |特許

原著論文

    Ochiai H, Hayashi T, Umeda M, Yoshimura M, Harada A, Shimizu Y, Nakano K, Saitoh N, Liu Z, Yamamoto T, Okamura T, Ohkawa Y, Kimura H and Nikaido I
    Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells
    Science Advances, in press, 2020
    Yaguchi S, Yaguchi J, Suzuki H, Kinjo S, Kiyomoto M, Ikeo K and Yamamoto T
    Establishment of homozygous knock-out sea urchins
    Current Biology, in press, 2020
    Miyamoto T, Hosoba K, Itabashi T, Iwane AH, Akutsu SN, Ochiai H, Saito Y, Yamamoto T and Matsuura S
    Insufficiency of ciliary cholesterol in hereditary Zellweger syndrome
    The EMBO Journal, in press, 2020
    Teratake Y, Takashina T, Iijima K, Sakuma T, Yamamoto T and Ishizaka Y
    Development of a protein-based system for transient epigenetic repression of immune checkpoint molecule and enhancement of antitumour activity of natural killer cells
    British Journal of Cancer, in press, 2020
    Tanigawa S, Naganuma H, Kaku T, Era T, Sakuma T, Yamamoto, Taguchi A, Nishinakamura R
    Activin Is Superior to BMP7 for Efficient Maintenance of Human iPSC-Derived Nephron Progenitors
    Stem Cell Reports, in press, 2019
    Liu D, Awazu A, Sakuma T, Yamamoto T, Sakamoto N
    Establishment of knockout adult sea urchins by using a CRISPR-Cas9 system
    Development Growth & Differentiation, in press, 2019
    Konishi S, Tanaka N, Mashimo T, Yamamoto T, Sakuma T, Kaneko T, Tanaka M, Izawa T, Yamate J and Kuwamura M
    Pathological characteristics of Ccdc85c knockout rats: a rat model of genetic hydrocephalus
    Experimental Animals, in press, 2019
    Li J, Dong A, Saydaminova K, Chang HZ, Wang G, Ochiai H, YamamotoT, Pertsinidis A
    Single-molecule nanoscopy elucidates RNA Polymerase II transcription at single genes in live cells
    Cell, in press, 2019
    Watanabe M, Nakano K, Uchikura A, Matsunari H, Yashima S, Umeyama K, Takayanagi S, Sakuma T, Yamamoto T, Morita S, Horii T, Hatada I, Nishinakamura R, Nakauchi H, Nagashima H
    Anephrogenic phenotype induced by SALL1 gene knockout in pigs
    Scientific Reports, 9(1):8016, 2019
    Takimoto A, Kokubu C, Watanabe H, Sakuma T, Yamamoto T, Kondoh G, Hiraki Y and Shukunami C
    Differential transactivation of the upstream aggrecan enhancer regulated by PAX1/9 depends on SOX9-driven transactivation
    Scientific Reports, in press, 2019
    Kohara H, Utsugisawa T, Sakamoto C, Hirose L, Ogawa Y, Ogura H, Sugawara A, Aoki T, Iwasaki T, Asai T, Doisaki S, Okuno Y, Muramatsu H, Abe T, Kurita R, Miyamoto S, Sakuma T, Shiba M, Yamamoto T, Ohga S, Yoshida K, Ogawa S, Ito E, Kojima S, Kanno H, Tani K
    KLF1 Mutation E325K Induces Cell-cycle Arrest in Erythroid Cells Differentiated from Congenital Dyserythropoietic Anemia (CDA) Patient-specific Induced Pluripotent Stem Cells
    Experimental Hematology, in press, 2019
    Tsuda M, Ogawa S, Ooka M, Kobayashi K, Hirota K, Wakasugi M, Matsunaga T, Sakuma T, Yamamoto T, Chikuma S, Sasanuma H, Debatisse M, Doherty AJ, Fuchs RP, Takeda S.
    PDIP38/PolDIP2 controls the DNA damage tolerance pathways by increasing the relative usage of translesion DNA synthesis over template switching
    PLoS One, 14(3):e0213383, 2019
    Takahashi F, Igarashi K, Takimura Y and Yamamoto T
    Elucidation of secondary alcohol metabolism in Starmerella bombicola and contribution of primary alcohol oxidase FAO1
    FEMS Yeast Res, in press, 2019
    Kazuki Y, Kobayashi K, Hirabayashi M, Abe S, Kajitani N, Kazuki K, Takehara S, Takiguchi M, Satoh D, Kuze J, Sakuma T, Kaneko T, Mashimo T, Osamura M, Hashimoto M, WakatsukiR, Hirashima R, Fujiwara R, Deguchi T, Kurihara A, Tsukazaki Y, Senda N, Yamamoto T, Scheer N and Oshimura M
    Humanized UGT2 and CYP3A transchromosomic rats for improved prediction of human drug metabolism
    Proc Natl Acad Sci U S A, in press, 2019
    Nishitani A, Kunisawa N, Sugimura T, Sato K, Yoshida Y, Suzuki T, Sakuma T, Yamamoto T, Asano M, Saito Y, Ohno Y and Kuramoto T
    Loss of HCN1 subunits causes absence epilepsy in rats
    Brain Research, 1706:209-217, 2019
    Harata A, Hirakawa M, Sakuma T, Yamamoto T and Hashimoto C
    Nucleotide receptor P2RY4 is required for head formation via induction and maintenance of head organizer in Xenopus laevis
    Development Growth & Differentiation, 61(2):186-197, 2019


総説・著書

    佐久間哲史、山本 卓
    CRISPR最新ツールボックス
    実験医学、羊土社(2021)
    山本 卓
    ゲノム編集とはなにか、講談社ブルーバックス(2020)
    山本 卓、佐久間 哲史
    ゲノム編集実験スタンダード、羊土社(2019)
    山本 卓
    ゲノム編集の基礎
    ゲノム編集の新技術、細胞The CELL(ニューサイエンス社), 51(3):108-109(2019)
    佐久間哲史
    エフェクター集積による次世代ゲノム編集
    ゲノム編集の新技術、細胞The CELL(ニューサイエンス社), 51(3):110-113(2019)
    山本 卓
    ゲノム編集の現状と課題
    遺伝子医学、メディカルドゥ, 9(1):20-24(2019)
    山本 卓
    ゲノム編集の歴史と基礎
    THE CHEMICAL TIMES、関東化学, 251(1):3-6(2019)
    山本 卓
    医療や創薬、バイオ燃料、農畜産物の品種改良や開発に世界が注目するゲノム編集(下)
    科学機器, 847(2019)
    山本 卓著
    ゲノム編集の基本原理と応用、裳華房(2018)


特許

    鈴木賢一、坂根祐人、佐久間哲史、山本 卓
    核酸挿入用ベクター、PCT/JP2014/079515 (2014)